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  Vitamin B3, also known as Vitamin PP (for Pellagra Preventing), is a water-soluble vitamin, which groups two molecules of similar biological activity, niacin and niacinamide. Its beneficial effects for anti-age applications have been highlighted in many scientific publications.Various studies show the ability of this vitamin to stimulate collagen synthesis and to reinforce the barrier function of the skin. It increases the levels of free fatty acids and ceramides, and deeply hydrates. It produces a marked improvement in the appearance of fine lines and wrinkles. Improved barrier function may be the mechanism by which it reduces redness/ blotchiness (in Reversa anti-redness soothing care).Niacinamide has a strong ability to interfere in the pigmentation process, thus reducing the appearance of dark spots. It brightens and evens out skin tone, reduces pore size, maintains the natural hydration, promotes microcirculation, helps reduce the appearance of signs of past damage caused by external aggressions (free radicals, blue light), and has the exceptional ability to improve the performance of many active ingredients.Niacinamide reduces redness, dryness, and irritation caused by bacteria that live in the clogged pores of acne pimples. It also provides powerful anti-inflammatory properties and antioxidant activity. It improves the microbiome and increases the production of natural antimicrobial peptides in the skin. In the Eye Care for puffiness and dark circles formulation, its activity on microcirculation is particularly interesting. Niacinamide helps reinforce the structure of the basal layer of the blood vessels, via its action on collagen synthesis. It helps maintain or restore a normal blood flow in capillaries via its vasculoprotective action, reducing the appearance of puffiness and dark circles under the eyes.

Product Performance The very core of our work is happening in our lab. In this space, we focus every day on finding the perfect balance between science and nature to infuse the result into our products. We translate our passion for healthy skin into high-performing formulas, time-saving routines, active blends and efficient solutions for all of your skin concerns. Here you’ll find a glossary of our skincare ingredients and product technology. 3D HYALURONIC ACID (HA) COMPLEX (6)-paradol Agefinity™ Alaria esculenta algae extract Ash tree bark extract Avobenzone (UVA filter) and octocrylene, octinoxate and octisalate (UVB filters) β-Glucan BIOMIMETIC NONAPEPTIDE-1 Canadian glacial oceanic mineral water Canadian chaga extract Centella Asiatica Chlorophyllin CRANBERRY-DERIVED NATURAL BIOPEPTIDES Dragon Fruit Extract Fragmented hyaluronic acid Glycolic acid Goji stem cell extract Hyaluronic acid INDIAN GENTIAN LEAF EXTRACT Isoflavones Malachite extract Matrixyl® Synthe’6™ Nonapeptide-1 Murunga Plum Extract Organic silicon Panthenol Pineapple Extract (Bromelian) Pisum sativum extract PLANT-BASED EPIDERMAL GROWTH FACTOR (EGF) PLANT-BASED POLYPEPTIDE PREBIOTIC PEPTIDE Retinol Rose water Rumex occidentalis extract Salicylic acid Shea butter Spirulina Tasmanian berry extract Teavigo® green tea extract Teprenone Time-release Glyco-comfort system™ Vigna aconitifolia seed extract Vitamin B3 (Niacinamide) Vitamin C Vitamin E Watermelon Extract Wild yam root extract Witch Hazel Water Yeast extract 3D HYALURONIC ACID (HA) COMPLEX Containing 6 sizes of HA, the 3D hyaluronic acid complex creates a three-dimensional structure to effectively trap water, plump skin and give it a youthful glow. Composed of molecules of different molecular weights, it quickly exerts its moisturizing effect for more than 24 hours, on the surface and in the deeper layers of the skin, while stimulating the production of natural HA. It also improves the suppleness of the skin and forms a protective film on its surface against external aggressions. It works at all levels. Glycolic acid A flagship ingredient for Reversa. Glycolic acid is an alpha hydroxy acid (AHA) derived from sugar cane. It has the ability to penetrate skin surface layers due to its small molecular size. Glycolic acid stimulates exfoliation and cell regeneration, leaving skin looking smoother and healthier. It effectively unglues the outer layer of dead cells and helps increase cell turnover, thus allowing healthier cells to rise to the surface of the skin more quickly than they would normally. Using glycolic acid will bring numerous benefits to the skin: Improvement in skin texture and colour Improvement in the appearance of dry, thickened, sun-damaged skin Better skin hydration Fresher, rejuvenated complexion Reduction in the appearance of wrinkles and age spots Unclogging of pores Normalization of the skin surface layers Salicylic acid Salicylic acid is a ß-hydroxy acid (BHA) used for its keratolytic and comedolytic properties. Oil-soluble, it exfoliates the surface of the skin and can penetrate epidermal lipids and sebaceous secretions. This characteristic makes it an especially effective ingredient to treat acne. It dries and helps clear up acne pimples and allows skin to heal. It deeply cleanses pores and eliminates blackheads, which tightens pores and makes them less visible. Its antibacterial action helps reduce acne-causing bacteria. It also reduces inflammation and redness. Time-release Glyco-comfort system™ All Reversa products containing glycolic acid feature the patented Time-release Glyco-comfort system™. This unique delivery system combines glycolic acid with an amino acid called arginine and the skin protectant allantoin. Glycolic acid is then released from the molecular complex over a longer period of time, which allows for improved skin tolerance. There is also a marked improvement in the formula’s moisturizing properties. Dermatologists readily recommend using glycolic acid because no other anti-aging cosmetic ingredient is supported by such a vast amount of scientific studies. And with Reversa’s patented Time-release Glyco-comfort system™, all skin types—even sensitive ones—can benefit from the remarkable anti-aging properties of glycolic acid. Matrixyl® Synthe’6™ Matrixyl® Synthe’6™ peptide was designed to provide a simple and non-invasive solution to the problem of skin aging. Its active ingredient, Pal-KMO2K peptide, provides visible, proven filling and anti-wrinkle effects on the epidermis, the dermal-epidermal junction and the dermis. It boosts the synthesis of 6 skin-rebuilding essentials, which are collagens I, III and IV, hyaluronic acid, fibronectin and laminin-5. The results of in vitro tests demonstrated a mechanism of action that leads to facial wrinkle smoothing by promoting a restructuring of the cutaneous tissues. Matrixyl® Synthe’6™, by stimulating the synthesis of 6 component molecules, demonstrates visibly effective smoothing of facial wrinkles. Agefinity™, a mannose-6-phosphate complex A real biomimetic, green and natural source of energy used to generate energy in the skin cells, helps reorganize the dermal matrix. Its action results in a reduction of the appearance of face, eye contour, neck and décolleté wrinkles, including tech wrinkles, a reshape of the Y zone (i.e. lower face and neck) and a reduction of visible dark spots.  Agefinity™ is a trademark of Givaudan. Avobenzone (UVA filter) and octocrylene, octinoxate and octisalate (UVB Filters) Avobenzone is a UVA filter. Unlike most other organic UVA filters, it provides broad-spectrum protection, including the longer wavelength UVA-I (340—400 nm). Most UV radiation that reaches Earth is in the form of UVA. Damaging UVA rays penetrate the epidermis and dermis more deeply than UVB rays. Clinical studies have demonstrated that chronic exposure to UVA can cause structural cell damage and possibly even lead to cancer. UVA rays damage the collagen and elastic fibres that give skin its shape, definition and suppleness. Exposure to UVA rays leads to wrinkling and, eventually, premature skin aging. When combined with UVB filters, it is possible to formulate a skin care product that provides broad-spectrum skin protection and helps prevent the formation of fine lines, wrinkles, age spots and potential skin cancer. (6)-paradol A new-generation multipurpose super antioxidant that protects the dermis and the epidermis from damage caused by chemical products, pollution and UV rays. It soothes irritation and redness while stimulating the production of hyaluronic acid. Alaria esculenta algae extract This extract from brown algae Alaria esculenta offers many important anti-aging benefits, which were scientifically proven by in vivo and in vitro testing: Stimulates hyaluronic acid synthesis Reinforces the hydrolipidic barrier Moisturizes in-depth Anti-collagenase and anti-elastase activity to preserve skin elasticity and skin suppleness by reducing elastin and collagen degradation Important antioxidant activity Free radical scavenger This extract is Ecocert compliant. Ash tree bark extract The high Ash (Fraxinus excelsior) is a large common tree found in European forests. Its height of up to 40 meters attracts lightning. Its bark contains esculin and fraxin, two heterosides known to actively decrease the permeability of blood capillaries. This activity, known as vitamin P activity (P for permeability), confers a veinotonic and vasculoprotective action to the product. Fraxin and esculin also present antioxidant activity to help protect the blood capillaries but also to fight against the degradation of haemoglobin into colored compounds and thus reduce coloration under the eyes. β-Glucan β-Glucan is a polysaccharide (complex carbohydrate) isolated from the cell wall of baker’s yeast. This biological agent increases resistance to UV-induced oxidative stress while stimulating the skin’s natural defence mechanisms. Although it is not an antioxidant molecule by itself, β-Glucan complements one or both of the antioxidants contained in the Reversa antioxidant booster serum [redirect to product page] (EGCG and vitamin E). Studies have also shown that β-Glucan brings important anti-aging benefits to the skin, such as improvement in firmness and a reduction of eye contour wrinkle depth. BIOMIMETIC NONAPEPTIDE-1 This peptide, identical to a peptide naturally present in the skin, helps limit the overproduction of melanin in a reversible and safe approach. In synergy with niacinamide, this duo of ingredients helps to effectively reduce the appearance of dark spots, leaving the complexion clearer and brighter. Canadian glacial oceanic mineral water Extracted from the mineral-rich clay which deposits along the Northern Pacific Coast in British Columbia, the water retains the complex mineral composition of the clay. Mineralizes the skin with naturally-balanced minerals and trace minerals (e.g. calcium, magnesium and sulfur). Increases moisture. Canadian chaga extract This Canadian mushroom extract channels its adaptogenic and anti-inflammatory qualities to improve skin barrier function and strengthen the skin’s defences. It provides comfort and protection to the fragile and sensitive eye contour area. It has been shown to be effective in reducing skin redness, providing a brighter look and reducing the appearance of dark circles and wrinkles. It soothes skin and reduces signs of fatigue. CRANBERRY-DERIVED NATURAL BIOPEPTIDES Derived from cranberries grown in Quebec using an eco-responsible approach, these biopeptides have the ability to act on several biological targets. They show powerful anti-aging efficacy: they reinforce the epidermal barrier function, reduce the volume and appearance of wrinkles and crow’s feet. Their activity is comparable to that of retinol, without potentially irritating effects. Fragmented hyaluronic acid This glycosaminoglycan (GAG) of small molecular weight penetrates deeply to hydrate and plump the skin. Goji stem cell extract By helping to overcome the lack of collagen and elastin in the skin, the goji stem cell extract leads to a reduction of the appearance of wrinkles and cutaneous sagging. The oval of the face looks better defined and rejuvenated.   INDIAN GENTIAN LEAF EXTRACT This extract improves the cohesion between the different layers of the skin by stimulating the production of several proteins essential to its proper functioning and to epidermal regeneration. It reduces skin roughness and the appearance ofwrinkles, including vertical wrinkles, like those around the lips.   Isoflavones Soy isoflavones are derived from soy and help keep skin young looking. Epidemiological studies have demonstrated that diets rich in soy products, as they are in Asian countries, are closely linked to lower incidences of breast cancer and cancer of the uterus, cardiovascular disease and postmenopausal symptoms. It is now generally accepted that such properties are due to isoflavones, a class of plant compounds that is particularly abundant in soybeans. Isoflavones interfere with cell metabolism. In the skin, they’ve been shown to stimulate the production of the skin’s structural components (collagens) and to inhibit matrix metallo-proteinases (enzymes that degrade the underlying network of proteins that make up the skin’s support layer). Hyaluronic acid Hyaluronic acid is a natural component of the skin’s support tissue that plays an important role in skin hydration. It occupies the space between the collagen and elastin fibres. Through the natural process of aging—or through exposure to environmental factors like sunlight—the quantity and quality of hyaluronic acid diminishes, which causes dry skin and wrinkles. Hyaluronic acid is among the best moisturizers available. It retains up to 1,000 times its weight of water in the intercellular matrix. Its moisture retention properties are higher than any other natural or synthetic polymer. Hyaluronic acid has a long-lasting moisturizing effect and is essential for skin repair and regeneration. Malachite extract Rich in copper, has a strong antioxidant activity as well as a detoxifying action. Murunga Plum Extract Murunga plum is a superfruit which contains a higher concentration of vitamin C than most other fruits.Thus, this extract has a very strong antioxidant activity, it helps reduce skin damage caused by oxidative stress and also induces the synthesis of collagen and hyaluronic acid. In addition to protecting and strengthening the skin, which reduces the appearance of signs of aging, it boosts radiance and evens out skin tone.   Nonapeptide-1 This cell-energizing peptide helps strengthen the skin barrier and improve skin hydration while increasing blood flow and microcirculation. Through its anti-fatigue and anti-aging effects, it improves the complexion and increases the luminosity of the face. It also reduces the appearance of lines and wrinkles. Organic silicon Silicon (Si) in its organic form is one of the components of the extracellular matrix: it is found in elastin, collagen and also glycosaminoglycans, of which it stimulates the synthesis. Silicon is also an important constituent of the arterial wall. It helps reinforce the structure and elasticity of the vessels, mainly by interaction with collagen and the elastin fibres. It functions as a cross-linking agent, restructuring the fibres of collagen and elastin and providing strength, flexibility and resilience to connective tissues. Organic silicon helps reinforce the structure of blood capillaries. Panthenol Pro-vitamin B5, which protects skin barrier function and reduces trans-epidermal water loss. Pisum sativum extract An active botanical extract derived from seeds of Pisum sativum L., pea extract keeps specific enzymes known as proteases from degrading skin proteins such as collagen and elastin, which are responsible for giving skin its firmness and elasticity. It can therefore protect collagen and elastin against the damaging effects of proteases activated by aging and through different types of skin abuse (UV, chemical, immunological, etc.) Used in skin care products, pea extract acts as an anti-enzyme complex and gives the skin its firmness and elasticity. A clinical study has demonstrated significant improvement in skin elasticity (+16.7%) after just three weeks of treatment. In combination with sucrose dilaurate, studies have shown that pea extract also produces a strong inhibition of tyrosinase activity, thereby significantly reducing melanogenesis (i.e. melanin production). As a result, brown spots are less visible, less numerous and smaller.   PLANT-BASED EPIDERMAL GROWTH FACTOR (EGF) EGF is a repairing peptide that mimics a protein naturally found in the skin and whose production decreases from the twenties, thus promoting a slower skin renewal process and the appearance of fine lines and wrinkles. EGF helps support the natural production of collagen, elastin and hyaluronic acid. It is also used in medicine to help regenerate the skin of burn victims. Of plant origin, this EGF is obtained from non-genetically modified Nicotiana benthamiana. It helps stimulate skin regeneration and restructuring, restores and maintains hydration, firmness and natural elasticity, strengthens the skin and boosts its radiance. It is a key ingredient for maintaining smooth, healthy and youthful skin. PLANT-BASED POLYPEPTIDE This biomimetic polypeptide mimics a specific cell growth factor in the body. It stimulates the synthesis of skin proteins and lipids, thereby improving firmness, elasticity and moisture retention, while supporting the overall integrity of the skin. It visibly reduces pore size and provides retinol-like activity, which helps delay the appearance of visible signs of skin aging. PREBIOTIC PEPTIDE This prebiotic increases the quantity of beneficial skin bacteria, while promoting diversity and a better balance of the microbiota. It also helps improve the integrity and barrier function of the skin, improves its immune response and helps prevent dehydration. Also evaluated on hands damaged by the use of disinfectant products, it has been shown effective in reducing excessive desquamation, moisturizing them and providing increased softness. Retinol A form of vitamin A that stimulates cell renewal, as well as collagen, elastin, and hyaluronic acid synthesis. It reduces the appearance of wrinkles, improves the firmness and suppleness of the skin. It regulates melanin synthesis, which reduces dark spots. Encapsulation in biodegradable polyurethane microspheres allows a controlled release of retinol while minimizing its irritant side. Rose water Organic rose distillate with astringent and toning properties. Rumex occidentalis extract Rumex extract is derived from plants of the Rumex genus, native to the Canadian Prairies. This abundant plant is easily recognized by the deep, rust-coloured seeds that colour the fields from early summer through late fall. Rumex extract is a highly effective inhibitor of tyrosinase, an enzyme present in both human skin and plant tissue. Tyrosinase inhibition reduces the formation of unwanted pigmentation and improves skin tone. Rumex extract has been shown to be effective in reducing the appearance of age spots. Shea Butter Shea butter is an excellent hydrating, antioxidant and anti-inflammatory ingredient for softening, nourishing and protecting the skin. It increases moisture retention in the skin, resulting in revitalized skin. Tasmanian berry extract A natural ingredient with anti-inflammatory and antioxidant properties. It provides immediate relief from irritation and optimal skin comfort. Teavigo® green tea extract Teavigo® is the purest form of green tea extract. It contains a high concentration of EGCG (epigallocatechin gallate), a potent antioxidant from the family of polyphenols (a chemical substance found in plants). It is considered one of the main elements responsible for the numerous health benefits of green tea. When applied topically, EGCG triggers anti-inflammatory activity and neutralizes free radicals that are produced when skin is exposed to pollution or other environmental hazards such as UV radiation known to cause oxidative stress. Teprenone Teprenone is a synthetic bio-mimetic molecule obtained from natural plant constituents such as geranylgeraniol (as starting material). It is a pluripotent active ingredient able to act as a cell facilitator but also on cell repair. Teprenone closely resembles physiological geranylgeranyl phosphate. It restores the functionality of young skin to old and tired skin, resulting in a change of appearance. Its anti-aging properties were rigorously validated by in vitro and in vivo studies. Vigna aconitifolia seed extract Vigna aconitifolia seed extract is a botanical alternative to retinol: its effects are similar, with a comparable mechanism of action, but skin tolerance and stability are superior. Clinical studies have shown that it stimulates epidermis cell renewal and collagen synthesis, thereby reducing wrinkles. It acts on both the epidermis and dermis to fight the effects of aging. Vitamin B3 (Niacinamide) Vitamin B3, also known as Vitamin PP (for Pellagra Preventing), is a water-soluble vitamin, which groups two molecules of similar biological activity, niacin and niacinamide. Its beneficial effects for anti-age applications have been highlighted in many scientific publications.Various studies show the ability of this vitamin to stimulate collagen synthesis and to reinforce the barrier function of the skin. It increases the levels of free fatty acids and ceramides, and deeply hydrates. It produces a marked improvement in the appearance of fine lines and wrinkles. Improved barrier function may be the mechanism by which it reduces redness/ blotchiness (in Reversa anti-redness soothing care).Niacinamide has a strong ability to interfere in the pigmentation process, thus reducing the appearance of dark spots. It brightens and evens out skin tone, reduces pore size, maintains the natural hydration, promotes microcirculation, helps reduce the appearance of signs of past damage caused by external aggressions (free radicals, blue light), and has the exceptional ability to improve the performance of many active ingredients.Niacinamide reduces redness, dryness, and irritation caused by bacteria that live in the clogged pores of acne pimples. It also provides powerful anti-inflammatory properties and antioxidant activity. It improves the microbiome and increases the production of natural antimicrobial peptides in the skin. In the Eye Care for puffiness and dark circles formulation, its activity on microcirculation is particularly interesting. Niacinamide helps reinforce the structure of the basal layer of the blood vessels, via its action on collagen synthesis. It helps maintain or restore a normal blood flow in capillaries via its vasculoprotective action, reducing the appearance of puffiness and dark circles under the eyes. Vitamin C Vitamin C is a powerful antioxidant that neutralizes free radicals produced by exposure to UV rays and to a polluted environment, by stress and various other causes. Free radicals are responsible for premature aging of the skin. Vitamin C stimulates collagen synthesis, which brings multiple anti-aging benefits: reduction of lines and wrinkles, improvement in skin firmness and elasticity. It reduces the production of melanin, the pigment causing brown spots, by inhibiting the action of tyrosinase enzyme and by other means. Vitamin C is an exceptional, safe and effective anti-aging ingredient that reduces the appearance of signs of aging, unifies complexion and brings a real radiance boost. Vitamin E The central role of vitamin E acetate is as an in vivo antioxidant. There is considerable evidence that topically applied vitamin E plays a critical role in protecting body cells and tissues from damage caused by the free radicals generated by natural body processes and environmental stresses. Topical application is extremely important, because only low levels of vitamin E are present in the epidermis and dermis. Vitamin E is depleted by UV light and ozone. Its most important attributes are that it: Moisturizes skin from within Cumulatively enhances skin smoothness Soothes and aids in tissue repair (wound healing) Protects skin from environmental stress Helps block lipid peroxidation (which can cause cell membrane damage) through its in vivo antioxidant function Lowers erythema (redness), edema and skin sensitivity following UVB exposure Watermelon Extract Watermelon extract is an exceptional moisturizer for the skin, it promotes cell regeneration and helps strenghten the natural defense mechanism against harmful environmental effects. In addition to improving the elasticity of the skin, it brings a boost of radiance. Wild yam root extract Wild yam is a plant indigenous to the eastern and central regions of the United States. An important constituent of the yam root is the steroid saponin diosgenin, a molecule that is an incubator for the formation of the hormone progesterone. The lipid balance of the skin is regulated at a hormonal level. As hormone activity decreases, lipid-cell proliferation of the skin decreases. In skin care products, wild yam is used to improve the skin lipid content in mature skin. Yeast extract A natural ingredient, rich in glucomannans (high molecular weight polysaccharides) and able to combat harmful environmental stress.   Spirulina Spirulina is a bioactive microalgae with many health benefits. Its main components are proteins, carbohydrates and fats. It has super antioxidant, revitalizing and remineralizing properties. This seaweed is also a rich source of many valuable compounds, such as carotenoids, chlorophyll, as well as several minerals (potassium, calcium, magnesium, selenium, iron and zinc) and vitamins (including vitamin B which is the most abundant). When applied to the skin, spirulina shows powerful anti-aging properties, it improves the barrier function, protects and brightens the skin, promotes healing. It also provides antioxidant and anti-acne properties mainly via the inhibition of C. acnes growth.   Centella Asiatica Extract Native to the heart of Madagascar, tiger grass is collected in a sustainable and eco-responsible way. Rich in madecassoside, Centella asiatica extract provides a soothing and anti-redness effect helping to relieve sensitive skin, in addition to improving cell viability and promoting healing. Centella asiatica extract works deep into the skin to restore its balance, it enhances radiance and luminosity. In addition to providing an immediate and long-lasting glow, it controls the keratinization process, protects the collagen network and improves cell viability. It is a natural extract with antioxidant properties, an immediate skin perfector! polysaccharides) and able to combat harmful environmental stress. Witch Hazel Water This distillate is prepared from the recently cut and partially dried branches of the Hamamelis virginiana plant, without denatured alcohol. Ideal for reducing irritation and discomfort of sensitive skin, witch hazel water provides astringent, antioxidant, soothing, toning and vasoconstrictive properties to the skin. It helps to detoxify the cells, and promotes the regeneration of the epidermis. It also helps eliminate excess sebum in oily, acne-prone skin. Pineapple Extract (Bromelian) Pineapple is a great source of natural enzymes, vitamin C, alpha hydroxy acids (AHAs) such as glycolic and citric acids. Pineapple extract contains vitamin B which improves skin barrier function and reduces both irritation and redness. The extract is particularly rich in bromelain, a type of pure natural plant protease, recognized for its various regenerative properties, including its ability to promote healing, reduce inflammation and thus accelerate the healing of wounds. Bromelain has exfoliating activity, providing smooth, soft and luminous skin. Chlorophyllin It is a chlorophyll derivative that has several beneficial properties for the skin, including antibacterial, antioxidant and anti-inflammatory activities. It is useful to control the growth of C. acnes responsible for the inflammation of acne and thus prevent the appearance of acne pimples. It decreases the size of dilated pores and reduces the number of acne lesions. Dragon Fruit Extract The dragon fruit extract used in the Reversa skincare has been produced in respect of the environment by ensuring a minimal carbon footprint; fruits are obtained by hand pollination and harvested manually. The extract is obtained directly by squeezing the fruit, an extraction process without adding solvents or water. This superfruit is rich in water (80-90%), minerals, flavonoids, vitamins (including vitamin C), sugars and fibers. It provides prebiotic activity promoting the growth of beneficial bacteria for the skin, allowing them to better compete with harmful bacteria. By improving and balancing the skin microbiota, it thus provides a stronger, better protected skin barrier in order to make the skin healthier. The dragon fruit extract significantly decreases transepidermal water loss, it also provides a visible improvement in the complexion, an increase in luminosity and lightening of the skin. Proven as a prebiotic ingredient, it provides clearer, more radiant skin